GxPlex

Observation series — MHRA GxP Data Integrity Guidance and Definitions

← MHRA data integrity

157 observation(s) recorded. 157 carry an address; none is without one. 157 retained normalised text and hold a digest.

Each observation is addressed by this row’s identifier, the date it was observed, and its sequence within that date — the same key /api/v1/series.jsonl publishes as `sequence`, counted in the order the store recorded them.

This digest is a leaf of the integrity root, and the command that recomputes it is published at /verify/.

Every addressed record below carries its own citation, naming the day, the URL that answered, the response as recorded, and the digest where one exists. Where none exists the citation says so and asserts no digest.

The GXP-OBS statements on the field a column renders: Normalised textcontent_length · The document observation · GXP-OBS version 1What it records Characters of normalised content.What it does not claim It measures the normalisation, not the document, and it is not a measure of how much a document says.Absent or null means Written as 0 wherever no digest was taken. A 0 here is the absence of a measurement and never a measured empty document.In the glossary · GXP-OBS
Address Date Outcome Method Normalised text SHA-256 of normalised text
2026-07-31·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-07-31·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-07-31 (record 1 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-07-31-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-07-31·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-07-31·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-07-31·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-07-31 (record 2 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-07-31-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-07-31·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-07-31·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-07-31·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-07-31 (record 3 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-07-31-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-07-31·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-07-31·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-07-31·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-07-31 (record 4 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-07-31-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-07-31·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-07-31·5
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-07-31·5
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-07-31 (record 5 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-07-31-5
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-07-31·5; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-07-31·6
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-07-31·6
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-07-31 (record 6 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-07-31-6
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-07-31·6; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-01·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-01·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-01 (record 1 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-01-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-01·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-01·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-01·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-01 (record 2 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-01-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-01·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-01·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-01·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-01 (record 3 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02 — the day this
             observation was recorded, UTC. The day named above, 2026-08-01,
             is this record's local day; the two clocks differ for this
             record.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-01-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-01·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-02·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-02·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-02 (record 1 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-02-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-02·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-02·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-02·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-02 (record 2 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-02-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-02·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-02·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-02·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-02 (record 3 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-02-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-02·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-03·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-03·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-03 (record 1 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-03-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-03·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-03·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-03·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-03 (record 2 of that day)
Requested:   https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-03-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-03·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-03·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-03·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-03 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-03-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-03·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-04·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-04·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-04 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-04-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-04·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-04·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-04·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-04 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-04-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-04·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-05·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-05·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-05 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-05-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-05·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-05·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-05·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-05 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-05-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-05·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-05·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-05·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-05 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,354 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-05-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-05·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,354 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-06·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-06·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-06 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-06-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-06·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-06·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-06·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-06 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-06-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-06·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-07·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-07·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-07 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-07 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-07-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-07·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-08·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-08·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-08 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-08-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-08·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-08·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-08·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-08 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-08-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-08·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-08·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-08·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-08 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-08-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-08·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-08·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-08·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-08 (record 4 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-08-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-08·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 4 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·5
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·5
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 5 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-5
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·5; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·6
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·6
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 6 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-6
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·6; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·7
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·7
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 7 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-7
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·7; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-09·8
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-09·8
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-09 (record 8 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-09-8
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-09·8; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-10·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-10·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-10 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-10-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-10·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-10·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-10·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-10 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-10-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-10·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-10·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-10·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-10 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-10-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-10·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-10·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-10·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-10 (record 4 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-10-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-10·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-10·5
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-10·5
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-10 (record 5 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-10-5
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-10·5; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-10·6
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-10·6
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-10 (record 6 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-10-6
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-10·6; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-11·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-11·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-11 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-11-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-11·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-11·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-11·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-11 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-11-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-11·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-11·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-11·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-11 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-11-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-11·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,339 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,339 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,406 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,406 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,406 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,406 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 4 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,406 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,406 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·5
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·5
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 5 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,406 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-5
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·5; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,406 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·6
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·6
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 6 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-6
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·6; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·7
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·7
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 7 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-7
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·7; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·8
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·8
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 8 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-8
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·8; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-12·9
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-12·9
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-12 (record 9 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-12-9
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-12·9; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-13·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-13·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-13 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-13 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-13-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-13·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-14·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-14·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-14 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-14 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-14-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-14·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-15·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-15·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-15 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-15-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-15·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-15·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-15·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-15 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-15-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-15·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-15·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-15·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-15 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-15-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-15·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-16·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-16·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-16 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-16-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-16·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-16·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-16·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-16 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-16-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-16·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-16·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-16·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-16 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-16-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-16·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-16·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-16·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-16 (record 4 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-16-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-16·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-17·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-17·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-17 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-17 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-17-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-17·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-18·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-18·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-18 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,360 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-18 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-18-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-18·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,360 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-19·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-19·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-19 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-19 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-19-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-19·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-20·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-20·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-20 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-20 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-20-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-20·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-21·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-21·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-21 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-21 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-21-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-21·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-22·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-22·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-22 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-22 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-22-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-22·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-22·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-22·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-22 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-22 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-22-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-22·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-23·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-23·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-23 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-23 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-23-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-23·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-24·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-24·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-24 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-24 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-24-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-24·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-25·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-25·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-25 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-25 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-25-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-25·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-25·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-25·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-25 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-25 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-25-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-25·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-26·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-26·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-26 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-26 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-26-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-26·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-26·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-26·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-26 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-26 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-26-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-26·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-27·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-27·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-27 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-27 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-27-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-27·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-28·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-28·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-28 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-28 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-28-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-28·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-29·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-29·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-29 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-29-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-29·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-29·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-29·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-29 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-29-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-29·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-30·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-30·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-30 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-30-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-30·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-30·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-30·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-30 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-30-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-30·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-08-31·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-08-31·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-08-31 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-08-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-08-31-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-08-31·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-01·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-01·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-01 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,310 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-01-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-01·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,310 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-02·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-02·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-02 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,296 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-02-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-02·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,296 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-02·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-02·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-02 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,296 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-02-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-02·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,296 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-03·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-03·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-03 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,296 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-03-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-03·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,296 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-04·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-04·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-04 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,256 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-04-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-04·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,256 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-04·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-04·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-04 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-04-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-04·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·3
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·3
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 3 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-3
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·3; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·4
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·4
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 4 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-4
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·4; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·5
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·5
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 5 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-5
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·5; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·6
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·6
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 6 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-6
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·6; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·7
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·7
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 7 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-7
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·7; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·8
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·8
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 8 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-8
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·8; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-05·9
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-05·9
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-05 (record 9 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-05-9
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-05·9; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-06·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-06·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-06 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-06-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-06·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-07·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-07·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-07 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,313 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-07 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-07-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-07·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,313 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-08·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-08·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-08 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,347 bytes returned
Digest:      SHA-256 13971812bd5771b549c455d2e6e6b391f1326e76a2963d9cc1420c4af6e4a759
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-08-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-08·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,347 bytes returned · digest differed direct 3,708 chars 13971812bd5771b549c455d2e6e6b391f1326e76a2963d9cc1420c4af6e4a759
2026-09-09·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-09·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-09 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,348 bytes returned
Digest:      SHA-256 6903993ae01bf24f5fa45271e5d67fdd47f434bd5385e308bc543221cfdedf2e
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-09-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-09·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,348 bytes returned · digest differed direct 3,708 chars 6903993ae01bf24f5fa45271e5d67fdd47f434bd5385e308bc543221cfdedf2e
2026-09-10·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-10·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-10 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,348 bytes returned
Digest:      SHA-256 aadc8bf624987bca7860dca3b96436b8dff19961bcab5e7bba9ff930917994e1
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-10-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-10·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,348 bytes returned · digest differed direct 3,708 chars aadc8bf624987bca7860dca3b96436b8dff19961bcab5e7bba9ff930917994e1
2026-09-11·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-11·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-11 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,348 bytes returned
Digest:      SHA-256 9a0948cb5e5b50e0737685231546b3c985e79491f79d58e654c0dd985f1ee7d3
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-11-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-11·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,348 bytes returned · digest differed direct 3,708 chars 9a0948cb5e5b50e0737685231546b3c985e79491f79d58e654c0dd985f1ee7d3
2026-09-12·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-12·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-12 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,348 bytes returned
Digest:      SHA-256 5f23d775ccaa1f2ee6833192dfd82e0d55e736b50783dabd96407c52a44850de
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-12-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-12·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,348 bytes returned · digest differed direct 3,708 chars 5f23d775ccaa1f2ee6833192dfd82e0d55e736b50783dabd96407c52a44850de
2026-09-13·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-13·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-13 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,348 bytes returned
Digest:      SHA-256 f4ddeaad589b602d637088464edb2fb780becb2ae6ab22952e92a48c2b0304d2
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-13 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-13-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-13·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,348 bytes returned · digest differed direct 3,708 chars f4ddeaad589b602d637088464edb2fb780becb2ae6ab22952e92a48c2b0304d2
2026-09-14·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-14·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-14 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,348 bytes returned
Digest:      SHA-256 fe6722320c02845dd9b22e287d5bbac57ef1a30d65dfe5c3d0acf2e609eed772
             3,708 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-14 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-14-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-14·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,348 bytes returned · digest differed direct 3,708 chars fe6722320c02845dd9b22e287d5bbac57ef1a30d65dfe5c3d0acf2e609eed772
2026-09-15·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-15·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-15 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,351 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-15-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-15·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,351 bytes returned · digest differed direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-16·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-16·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-16 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,351 bytes returned
Digest:      SHA-256 c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
             3,661 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-16-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-16·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,351 bytes returned direct 3,661 chars c330704e7caaecdaf177bab279b28adc623ce786d6478774e9715b1f73c7229c
2026-09-17·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-17·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-17 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-17 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-17-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-17·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned · digest differed direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-18·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-18·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-18 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-18 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-18-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-18·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-19·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-19·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-19 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-19 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-19-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-19·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-20·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-20·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-20 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-20 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-20-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-20·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-21·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-21·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-21 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-21 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-21-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-21·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-22·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-22·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-22 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-22 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-22-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-22·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-23·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-23·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-23 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-23 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-23-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-23·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-24·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-24·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-24 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-24 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-24-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-24·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-25·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-25·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-25 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 76,405 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-25 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-25-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-25·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 76,405 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-26·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-26·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-26 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,098 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-26 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-26-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-26·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,098 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-27·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-27·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-27 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,098 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-27 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-27-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-27·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,098 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-28·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-28·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-28 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,098 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-28 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-28-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-28·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,098 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-29·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-29·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-29 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,098 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-29-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-29·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,098 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-09-30·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-09-30·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-09-30 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,098 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-09-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-09-30-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-09-30·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,098 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-01·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-01·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-01 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,032 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-01-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-01·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,032 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-01·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-01·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-01 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,099 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-01-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-01·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,099 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-02·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-02·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-02 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,099 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-02-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-02·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,099 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-03·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-03·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-03 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,099 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-03-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-03·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,099 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-04·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-04·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-04 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,099 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-04-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-04·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,099 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-05·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-05·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-05 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,099 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-05-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-05·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,099 bytes returned direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-06·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-06·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-06 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-06-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-06·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned · digest differed direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-07·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-07·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-07 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-07 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-07-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-07·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-08·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-08·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-08 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-08-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-08·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-09·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-09·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-09 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 75,099 bytes returned
Digest:      SHA-256 ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
             3,660 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-09-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-09·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 75,099 bytes returned · digest differed direct 3,660 chars ced856cd0b5a1c8e0e048231afd2fa76442c0ca13dabba883498be01087f588b
2026-10-10·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-10·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-10 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-10-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-10·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned · digest differed direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-11·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-11·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-11 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-11-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-11·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-11·2
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-11·2
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-11 (record 2 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-11-2
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-11·2; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-12·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-12·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-12 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-12-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-12·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-13·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-13·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-13 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-13 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-13-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-13·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-14·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-14·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-14 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-14 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-14-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-14·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-15·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-15·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-15 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,244 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-15-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-15·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,244 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-16·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-16·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-16 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-16-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-16·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-17·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-17·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-17 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-17 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-17-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-17·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-18·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-18·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-18 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-18 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-18-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-18·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-19·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-19·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-19 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-19 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-19-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-19·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-20·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-20·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-20 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-20 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-20-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-20·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-21·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-21·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-21 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-21 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-21-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-21·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-22·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-22·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-22 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-22 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-22-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-22·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-23·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-23·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-23 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-23 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-23-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-23·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-24·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-24·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-24 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-24 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-24-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-24·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-25·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-25·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-25 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-25 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-25-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-25·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-26·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-26·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-26 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-26 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-26-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-26·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-27·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-27·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-27 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-27 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-27-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-27·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-28·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-28·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-28 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-28 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-28-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-28·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-29·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-29·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-29 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-29-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-29·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-30·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-30·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-30 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-30-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-30·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-10-31·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-10-31·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-10-31 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-10-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-10-31-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-10-31·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-11-01·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-11-01·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-11-01 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-11-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-11-01-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-11-01·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
2026-11-02·1
Cite this observation 
GxPlex observation record mhra-data-integrity 2026-11-02·1
Document:    MHRA GxP Data Integrity Guidance and Definitions
Observed:    2026-11-02 (record 1 of that day)
Answered at: https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
Response:    HTTP 200, fetched direct, 74,243 bytes returned
Digest:      SHA-256 c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c
             3,586 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/how/; the command
             that recomputes a digest is published at
             https://gxplex.com/verify/.
Capture:     https://web.archive.org/web/20260802003255/https://www.gov.uk/government/publications/guidance-on-gxp-data-integrity
             (Internet Archive, submitted 2026-08-02, before this observation
             was recorded on 2026-11-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/mhra-data-integrity#obs-2026-11-02-1
Full record: https://gxplex.com/api/v1/series.jsonl
Bundle:      https://gxplex.com/api/v1/observation-bundle/mhra-data-integrity.json
             (this observation under key 2026-11-02·1; the bundle states what
             its proofs cover and its signature state)
 HTTP 200 · 74,243 bytes returned direct 3,586 chars c59c1f4d83779d0778c985a36975d15cc912ad37fe5edb15304cb8e31f73786c

Every record above is published untruncated at /api/v1/series.jsonl, which carries the same sequence these addresses are built from.