# Evidence packet — ISPE Pharma 4.0

Generated 2026-09-18. Packet version 1.
Published at https://gxplex.com/packet/ispe-pharma-4-0

This packet reports what a publisher published and when this record observed it. It carries no assessment of what the document requires and no reading of what any change means.

## Source

| field | value |
| --- | --- |
| id | ispe-pharma-4-0 |
| title | ISPE Pharma 4.0 programme outputs |
| jurisdiction | International |
| source url (asked) | https://ispe.org/initiatives/pharma-4.0 |
| answered url | — |
| observed cadence | quarterly |
| row | https://gxplex.com/r/ispe-pharma-4-0 |

## Publisher

| field | value |
| --- | --- |
| authority | International Society for Pharmaceutical Engineering |
| origin host | — |
| origin citation | — |
| standards body | — |
| standards body citation | — |

No origin host is recorded for this row. The authority named above is the body; the host is a fact about which origin answered, and this row does not carry one.

## Type

| field | value |
| --- | --- |
| class as stated by the publisher | — |
| read from | — |
| source kind, recorded here | document |
| source type, recorded here | document |
| record tier | core |

No class statement by the publisher is recorded for this row, so this packet states none. That is an absent reading rather than a document without a class.

## Lifecycle

| field | value |
| --- | --- |
| status | unknown |
| status qualifier | — |
| status as of | — |
| effective date | — |
| last changed | — |
| status read from | — |
| status withdrawn | — |
| status withdrawn on | — |
| decay class | frozen |
| frozen reason | no_public_document |

These are the dates the record holds for this document's own status. They state nothing about which products or activities the document reaches.

## Verification

| field | value |
| --- | --- |
| state | ▨ not re-checked |
| what the state states | no status recorded; each row states its reason |
| checked by | — |
| check date | — |
| last verified | — |

## Terms

| field | value |
| --- | --- |
| licence class | restricted |
| text retained here | yes |
| quotation appears in this record | no |
| snapshot retained here | yes |

## Observations with retained text

| first seen | seq | days | digest | class | answered at | bytes |
| --- | --- | --- | --- | --- | --- | --- |
| 2026-07-28 | 1 | 53 | 9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c | document | https://ispe.org/initiatives/pharma-4.0 | 6539 |

Digests recorded: 1. With retained text: 1. Without: 0. Series state: one-point.

One reading with retained text. Nothing has been observed to differ from it, and a comparison needs two.

## Changes

One entry per consecutive pair of retained readings, in the order this record first saw each digest. Every entry carries a measured difference or the first condition that refused one. A refused entry was never tested against the conditions after it.

No transition. One reading with retained text. Nothing has been observed to differ from it, and a comparison needs two.

## Integrity

| field | value |
| --- | --- |
| root | fd0980cf7ca42518ff7457b92b075df16163772d48d6f75e546b4869fe7bedab |
| leaves the root covers | 5393 |
| algorithm | SHA-256 over sorted `id\|date\|content_hash` lines, pairwise; an odd final node is promoted, never doubled. |
| fixed on | 2026-09-18 |
| root published at | https://gxplex.com/integrity/root.txt |
| leaves published at | https://gxplex.com/integrity/leaves.txt |
| the commands | https://gxplex.com/verify |
| leaf lines for this row | 53 |

The root is over every leaf line the record holds, not over the lines below. Reducing it needs the published file, which is served whole at the address named here together with the command that reduces it. These lines are this row's own slice of that file, copied verbatim.

```
ispe-pharma-4-0|2026-07-28|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-07-29|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-07-30|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-07-31|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-01|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-02|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-03|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-04|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-05|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-06|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-07|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-08|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-09|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-10|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-11|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-12|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-13|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-14|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-15|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-16|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-17|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-18|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-19|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-20|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-21|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-22|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-23|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-24|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-25|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-26|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-27|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-28|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-29|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-30|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-08-31|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-01|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-02|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-03|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-04|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-05|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-06|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-07|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-08|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-09|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-10|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-11|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-12|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-13|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-14|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-15|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-16|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-17|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
ispe-pharma-4-0|2026-09-18|9f72ebea62a50155c89390129a9c51c920de4d1ca6a8fc9a26f7e0de649c8f1c
```

## What this packet does not carry

- **the words that differ** — A count of a difference is in this packet; the words are not. They are a publisher's text, and this record checks borrowed text only on the surfaces it enumerates — a packet carrying spans under a key those checks do not read would be borrowed text nothing verifies. Each change names the comparison entry for the same pair, and says which of the two is at that address: the words, where a difference was measured and is inside the word ceiling; otherwise the same condition this entry names, with no text of the document.
- **this records own prose** — The row's summary and its account of an unresolved address are this archive's own voice. They are leads and not evidence, however accurate, because a faithful paraphrase is indistinguishable from evidence while remaining ours. They are published on the row's page and are not here.
- **any field that would characterise a change** — No score, no rank, no ordering by judgment, no reading of what a change means and no word for how much of it counts. A packet is evidence taken elsewhere, and a field characterising it would be an opinion with digests attached.
- **a recomputed root** — The integrity block states the root this record published and the leaf lines for this row. It computes no root of its own: two numbers this record produced, compared with each other, check nothing.

## The conditions, in the order they are evaluated

Counted over the 0 transition(s) above.

| condition | changes | what it states |
| --- | --- | --- |
| licence-restricted | not reached | No text from this document appears on this site, so no difference between two readings of it is shown either. The digests, the dates and the addresses are the record for this row. |
| licence-unread | not reached | No reading of the terms this source states is recorded for the row. That is an absent reading rather than an absent term, and the row is handled here exactly as a restricted one until a reading is recorded. |
| date-not-observed | not reached | No observation of this row on that day holds retained text. |
| date-not-unique | not reached | That day holds more than one distinct retained digest for this row, so a date alone does not name one observation. The addressed form — the day and the sequence within it — does. |
| one-point | not reached | Both dates resolve to the same observation. |
| referent-unclassified | not reached | The class of one of these observations could not be read, so neither was shown to be an observation of the document itself. |
| referent-class | not reached | One of these observations is not of the document. A listing page that names the document and the document are different subjects, and a difference between them is not a difference in the document. |
| referent-normalisation | not reached | These two digests were taken over different kinds of text — one over markup, one over prose extracted from a file — so the words they yield differ for a reason that is not the publisher’s. |
| referent-address | not reached | These two observations answered at different addresses. A difference between them is at least in part a difference between two pages. |
| text-not-retained | not reached | No normalised text is held here for one of these observations, so there is nothing on this side to compare. |
| snapshot-unreadable | not reached | Normalised text is recorded for one of these observations and could not be read from this record. |
| span-unverified | not reached | A span this comparison would have shown could not be found, word for word and in that order, in the retained text it was drawn from. The comparison is withheld rather than shown: a phrase assembled out of words a publisher did not write next to each other is a fabricated measurement of what the publisher wrote. |
| over-ceiling | not reached | A faithful difference is longer than the word ceiling this site publishes under. It is withheld whole rather than cut to fit: a shortened quote is a fabricated measurement of what a publisher wrote. The figures below are counts of the difference, not the difference. |

This row holds fewer than two readings with retained text, so no pair was formed and no condition was evaluated at all. Every condition is unreached here, which is a different fact from a condition that was evaluated and did not fire.

Word ceiling: 14.