GxPlex

Observation series — Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products

← FDA AI guidance

160 observation(s) recorded. 160 carry an address; none is without one. 160 retained normalised text and hold a digest.

2 of these records are left out of every count of the document series, and each says so in its own outcome cell below , each where the landing URL is a not-found path. 2 of them were hashed. Each stands in the store as it was written, with its address, its response and its digest; the annotation sits beside it and nothing was rewritten. The ruling is of , and the document series it governs is what the windows on FDA AI guidance count.

Each observation is addressed by this row’s identifier, the date it was observed, and its sequence within that date — the same key /api/v1/series.jsonl publishes as `sequence`, counted in the order the store recorded them.

This digest is a leaf of the integrity root, and the command that recomputes it is published at /verify.

Every addressed record below carries its own citation, naming the day, the URL that answered, the response as recorded, and the digest where one exists. Where none exists the citation says so and asserts no digest.

Address Date Outcome Method Normalised text SHA-256 of normalised text
2026-07-28·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 3 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 4 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 5 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 6 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 7 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 57,031 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 57,031 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·8
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·8
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 8 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-8
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·9
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·9
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 9 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-9
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-28·10
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-28·10
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-28 (record 10 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 57,031 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-28-10
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 57,031 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 3 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 4 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 5 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 6 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 7 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·8
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·8
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 8 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-8
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·9
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·9
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 9 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-9
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·10
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·10
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 10 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-10
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·11
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·11
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 11 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-11
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·12
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·12
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 12 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-12
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·13
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·13
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 13 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-13
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-29·14
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-29·14
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-29 (record 14 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-29-14
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 3 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 4 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 5 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 6 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 7 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·8
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·8
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 8 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-8
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·9
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·9
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 9 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-9
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·10
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·10
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 10 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-10
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·11
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·11
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 11 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-11
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·12
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·12
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 12 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-12
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·13
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·13
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 13 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-13
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·14
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·14
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 14 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-14
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·15
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·15
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 15 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-15
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·16
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·16
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 16 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-16
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·17
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·17
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 17 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,907 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-17
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,907 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·18
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·18
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 18 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-18
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-30·19
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-30·19
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-30 (record 19 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-30-19
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 3 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 4 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 5 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 6 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-07-31·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-07-31·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-07-31 (record 7 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-07-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-07-31-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-01·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-01·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-01 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,902 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-01-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,902 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-01·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-01·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-01 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,902 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-01-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,902 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-01·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-01·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-01 (record 3 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-01-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-02·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-02·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-02 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 57,029 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-02-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 57,029 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-02·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-02·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-02 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-02-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-02·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-02·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-02 (record 3 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-02-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-03·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-03·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-03 (record 1 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-03-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-03·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-03·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-03 (record 2 of that day)
Requested:   https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (no answering URL was recorded for this observation)
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-03-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-03·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-03·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-03 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-03-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-04·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-04·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-04 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,896 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-04-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,896 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-04·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-04·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-04 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,896 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-04-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,896 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-05·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-05·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-05 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-05-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-05·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-05·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-05 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-05-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-05·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-05·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-05 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-05-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-06·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-06·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-06 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-06-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-06·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-06·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-06 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-06-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-07·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-07·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-07 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,962 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-07 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-07-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,962 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-08·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-08·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-08 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-08-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-08·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-08·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-08 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-08-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-08·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-08·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-08 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-08-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-08·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-08·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-08 (record 4 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-08 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-08-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 57,025 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 57,025 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 4 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 5 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 6 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 7 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-09·8
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-09·8
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-09 (record 8 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,893 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-09 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-09-8
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,893 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-10·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-10·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-10 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-10-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-10·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-10·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-10 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-10-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-10·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-10·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-10 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-10-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-10·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-10·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-10 (record 4 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-10-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-10·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-10·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-10 (record 5 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,892 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-10 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-10-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,892 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-10·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-10·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-10 (record 6 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,904 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-10-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,904 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-11·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-11·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-11 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,904 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-11 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-11-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,904 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-11·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-11·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-11 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-11-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-11·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-11·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-11 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-11-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 4 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 5 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 6 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 7 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·8
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·8
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 8 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-8
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-12·9
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-12·9
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-12 (record 9 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,887 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-12 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-12-9
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,887 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-13·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-13·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-13 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,898 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-13 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-13-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,898 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-14·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-14·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-14 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,891 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-14 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-14-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,891 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-15·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-15·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-15 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,900 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-15-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,900 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-15·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-15·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-15 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,900 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-15-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,900 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-15·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-15·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-15 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,900 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-15 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-15-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,900 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-16·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-16·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-16 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-16-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-16·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-16·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-16 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-16-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-16·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-16·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-16 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-16-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-16·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-16·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-16 (record 4 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-16 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-16-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-17·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-17·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-17 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,897 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-17 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-17-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,897 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-18·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-18·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-18 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,895 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-18 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-18-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,895 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-19·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-19·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-19 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,903 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260728105147/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-07-28, before this observation
             was recorded on 2026-08-19 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-19-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,903 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-20·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-20·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-20 (record 1 of that day)
Answered at: https://www.fda.gov/about-fda/page-not-found
             (requested https://www.fda.gov/regulatory-information/search-fda-guidance-documents; the publisher redirected)
Response:    HTTP 200, fetched direct, 36,798 bytes returned
Digest:      SHA-256 088a7a37c55d7a9852343358802ebdfdf79d23a655f26e6fa4b056cce2ca1e37
             722 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260820080017/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-20 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-20-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 36,798 bytes returned · content changed · left out of every count of the document series direct 722 chars 088a7a37c55d7a9852343358802ebdfdf79d23a655f26e6fa4b056cce2ca1e37
2026-08-21·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-21·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-21 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,900 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-21-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,900 bytes returned · content changed direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-22·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-22·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-22 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,889 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-22 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-22-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,889 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-22·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-22·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-22 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,889 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-22 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-22-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,889 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-23·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-23·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-23 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,899 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-23 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-23-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,899 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-24·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-24·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-24 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,894 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-24 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-24-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,894 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-25·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-25·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-25 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,819 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-25 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-25-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,819 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-25·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-25·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-25 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,819 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-25 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-25-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,819 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-26·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-26·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-26 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,810 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-26 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-26-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,810 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-26·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-26·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-26 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,810 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260821080049/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-21, before this observation
             was recorded on 2026-08-26 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-26-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,810 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-27·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-27·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-27 (record 1 of that day)
Answered at: https://www.fda.gov/about-fda/page-not-found
             (requested https://www.fda.gov/regulatory-information/search-fda-guidance-documents; the publisher redirected)
Response:    HTTP 200, fetched direct, 36,798 bytes returned
Digest:      SHA-256 088a7a37c55d7a9852343358802ebdfdf79d23a655f26e6fa4b056cce2ca1e37
             722 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27 — the day this
             observation was recorded, UTC.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-27-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 36,798 bytes returned · content changed · left out of every count of the document series direct 722 chars 088a7a37c55d7a9852343358802ebdfdf79d23a655f26e6fa4b056cce2ca1e37
2026-08-28·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-28·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-28 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,822 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-08-28 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-28-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,822 bytes returned · content changed direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-29·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-29·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-29 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,817 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-08-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-29-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,817 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-29·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-29·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-29 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,817 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-08-29 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-29-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,817 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-30·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-30·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-30 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,812 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-08-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-30-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,812 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-30·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-30·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-30 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,812 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-08-30 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-30-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,812 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-08-31·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-08-31·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-08-31 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,827 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-08-31 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-08-31-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,827 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-01·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-01·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-01 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 28,012 bytes returned
Digest:      SHA-256 630bd27c7b423644b81cb207f479891c87987496d6a8d3a004def7b0f6473ea4
             27,492 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-01 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-01-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 28,012 bytes returned · content changed direct 27,492 chars 630bd27c7b423644b81cb207f479891c87987496d6a8d3a004def7b0f6473ea4
2026-09-02·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-02·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-02 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,312 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-02-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,312 bytes returned · content changed direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-02·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-02·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-02 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,312 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-02 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-02-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,312 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-03·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-03·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-03 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,302 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-03 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-03-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,302 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-04·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-04·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-04 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,316 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-04-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,316 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-04·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-04·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-04 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,316 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-04 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-04-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,316 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 2 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 3 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 4 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 5 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·6
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·6
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 6 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-6
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·7
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·7
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 7 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-7
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·8
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·8
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 8 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-8
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-05·9
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-05·9
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-05 (record 9 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,307 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-05 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-05-9
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,307 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-06·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-06·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-06 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,312 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-06 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-06-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,312 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-07·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-07·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-07 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,303 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Capture:     https://web.archive.org/web/20260827080058/https://www.fda.gov/regulatory-information/search-fda-guidance-documents
             (Internet Archive, submitted 2026-08-27, before this observation
             was recorded on 2026-09-07 UTC. NOT a capture of this
             observation.)
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-07-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,303 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-07·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-07·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-07 (record 2 of that day)
Answered at: https://www.fda.gov/media/184830/download
Response:    HTTP 200, fetched direct, 416,872 bytes returned
Digest:      SHA-256 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
             67,237 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-07-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 416,872 bytes returned direct 67,237 chars 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
2026-09-07·3
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-07·3
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-07 (record 3 of that day)
Answered at: https://www.fda.gov/media/184830/download
Response:    HTTP 200, fetched direct, 416,872 bytes returned
Digest:      SHA-256 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
             67,237 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-07-3
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 416,872 bytes returned direct 67,237 chars 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
2026-09-07·4
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-07·4
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-07 (record 4 of that day)
Answered at: https://www.fda.gov/media/184830/download
Response:    HTTP 200, fetched direct, 416,872 bytes returned
Digest:      SHA-256 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
             67,237 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-07-4
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 416,872 bytes returned direct 67,237 chars 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
2026-09-07·5
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-07·5
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-07 (record 5 of that day)
Answered at: https://www.fda.gov/media/184830/download
Response:    HTTP 200, fetched direct, 416,872 bytes returned
Digest:      SHA-256 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
             67,237 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-07-5
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 416,872 bytes returned direct 67,237 chars 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
2026-09-08·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-08·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-08 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,312 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-08-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,312 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-09·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-09·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-09 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,306 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-09-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,306 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-10·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-10·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-10 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,313 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-10-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,313 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-11·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-11·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-11 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,438 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-11-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,438 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-12·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-12·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-12 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,390 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-12-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,390 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-13·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-13·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-13 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,310 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-13-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,310 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-13·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-13·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-13 (record 2 of that day)
Answered at: https://www.fda.gov/media/184830/download
Response:    HTTP 200, fetched direct, 416,872 bytes returned
Digest:      SHA-256 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
             67,237 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-13-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 416,872 bytes returned direct 67,237 chars 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
2026-09-14·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-14·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-14 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,359 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-14-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,359 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-15·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-15·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-15 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,367 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-15-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,367 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-16·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-16·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-16 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,473 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-16-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,473 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-17·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-17·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-17 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,462 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-17-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,462 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-18·1
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-18·1
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-18 (record 1 of that day)
Answered at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents
Response:    HTTP 200, fetched direct, 56,469 bytes returned
Digest:      SHA-256 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
             4,795 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-18-1
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 56,469 bytes returned direct 4,795 chars 61d4603ff66e3a307239a38601161bb52bd5a679ef51125c220efd26572e187d
2026-09-18·2
Cite this observation 
GxPlex observation record fda-ai-guidance 2026-09-18·2
Document:    Considerations for the Use of Artificial Intelligence to Support Regulatory Decision-Making for Drug and Biological Products
Observed:    2026-09-18 (record 2 of that day)
Answered at: https://www.fda.gov/media/184830/download
Response:    HTTP 200, fetched direct, 416,872 bytes returned
Digest:      SHA-256 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4
             67,237 characters of normalised text.
             The digest is of the NORMALISED text, not of the bytes served:
             tags, scripts, navigation and volatile strings are removed before
             hashing, so hashing the source as served will not reproduce it.
             Normalisation is described at https://gxplex.com/methodology; the
             command that recomputes a digest is published at
             https://gxplex.com/verify.
Permalink:   https://gxplex.com/observations/fda-ai-guidance#obs-2026-09-18-2
Full record: https://gxplex.com/api/v1/series.jsonl
 HTTP 200 · 416,872 bytes returned direct 67,237 chars 5c61f4c6351dd8b91debbcc4566424f1084afe7fe55e032e00c05cbc8adf7ac4

Every record above is published untruncated at /api/v1/series.jsonl, which carries the same sequence these addresses are built from.